Ketamine | Sensory Seeking

Ketamine, a dissociative anesthetic developed in the 1960s, has a complex and evolving profile. Initially hailed for its safety and efficacy in surgical settings, its psychoactive properties soon became apparent, leading to recreational use and subsequent scheduling. In recent decades, a resurgence of interest has focused on its rapid antidepressant effects, particularly for treatment-resistant depression, with formulations like esketamine gaining FDA approval. This has sparked intense debate about its therapeutic potential, risks of abuse, and the ethical considerations surrounding its expanding applications.